Conjugated Estrogens Side Effects

conjugated estrogens can have more severe side effects, such as blurred vision, frequent infections, loss of bone mineral density, and decreased libido. Women taking conjugated estrogen may also experience psychological effects, such as memory loss and confusion.
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What is the risk of developing gallbladder disease with conjugated estrogens?

Conjugated Estrogens Side Effects

Conjugated estrogens are hormones that can help treat menopause symptoms in women. They’re also used to treat certain types of cancer in women and men. Despite the medical benefits, they can also carry risks and cause side effects.

Common Side Effects

Common side effects of conjugated estrogens include nausea, bloating, headache, and breast tenderness. These may last for a few days and then go away. Other common side effects may include:

  • Weight gain
  • Mood changes or an increased risk of depression
  • Decreased libido
  • Vaginal bleeding or spotting
  • Vaginal discharge
  • Breast enlargement
  • Hair loss
  • Swelling of your ankles, feet, or legs

Less Common Side Effects

Less common side effects of conjugated estrogens include:

  • Painful periods
  • High blood pressure
  • Gallbladder disease
  • Jaundice (yellowing of the eyes)
  • Fluid buildup in the abdomen
  • Difficulty sleeping

Frequently Asked Questions

Are conjugated estrogens dangerous?

Conjugated estrogens are not necessarily dangerous, but side effects can occur. Common side effects are mild and generally go away after a few days. However, it can cause more serious side effects in some people.

Can conjugated estrogens cause weight gain?

Weight gain can be a side effect of taking conjugated estrogens. It is not uncommon to gain a few pounds, but it is important to take any changes in weight seriously and speak to your doctor if you have any concerns.

How long do conjugated estrogens take to work?

The effects of conjugated estrogens can take up to two weeks to become noticeable. If you do not see any changes after that time period, talk to your doctor to discuss other options.


Conjugated estrogens are hormones used to treat menopause symptoms in women. Taking conjugated estrogens can cause various side effects, including common ones such as nausea, bloating, headache, and breast tenderness, as well as less common ones such as weight gain, high blood pressure, fluid buildup in the abdomen, and difficulty sleeping. It is important to speak to your doctor if you have any concerns or do not see a change in your symptoms after taking conjugated estrogens.